Fls2 pub12 pub13
WebPUB12 and PUB13 carry out the FLS2 ubiquitination after they are phosphorylated by BAK1, suggesting that BAK1 regulates the FLS2 degradation . Activity of the BAK1 and BIK1 kinases is negatively regulated by phosphatases, however this process may be attenuated upon perception of the pathogen-associated ligand. WebAs previously discussed, PUB12/PUB13-mediated ubiquitination of FLS2 is expected to modulate its intracellular trafficking (Lu et al., 2011). Since degradation of integral membrane proteins is mediated by the vacuole, …
Fls2 pub12 pub13
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WebRemarkably, Lu et al. (2011) recently reported that the PRR FLAGELLIN-SENSING2 (FLS2), a LRR receptor-like kinase , is a target of the E3 ligases PUB12 and PUB13 via … WebOct 21, 2024 · Encodes a U-box E3 ubiquitin ligase involved in ubiquitination of pattern recognition receptor FLS2. PUB12 armadillo/beta-catenin repeat protein [ (thale cress)] …
WebPharmacological inhibition of poly(ADP-ribose) polymerase (PARP) or loss of Arabidopsis thaliana PARG1 (poly(ADP-ribose) glycohydrolase) disrupt a subset of plant defenses. In the present study we examined the impact of altered poly(ADP-ribosyl)ation WebOct 21, 2024 · Encodes a U-box E3 ubiquitin ligase involved in ubiquitination of pattern recognition receptor FLS2. NEW Try the new Gene table Try the new Transcript table. …
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WebNov 28, 2024 · Consequently, FLS2 is ubiquitinated by PUB12/PUB13 and then degraded through a 26S proteasome pathway. In a similar manner, rice PRR Xa21 is negatively regulated by the protein phosphatase 2C and ubiquitinated by the RING-finger ubiquitin E3 ligase XB3 . However, in contrast to PUB12/PUB13, XB3 positively regulates Xa21 …
WebFeb 14, 2024 · Similar to pub13 mutants, pub12/13 double mutants showed altered responses to CO8 elicitation in ROS production and MAP kinase phosphorylation ... the mechanism of PUB13 regulation of FLS2 and … how to spice up frozen vegetablesWebThe data are shown as means T SEs from three replicates. Asterisk indicates a significant difference with P < 0.05 when compared with data from WT plants. (E) PUB12 and PUB13 promote FLS2 degradation. how to spice up ketchupWebFeb 5, 2024 · PUB12 and PUB13 were initially identified as BAK1-interacting E3 ligases that regulate FLS2 stability in flg22 signaling (14, 15). Recently, PUB12 and PUB13 were … re4 remake cheap keyWebMay 8, 2024 · The Arabidopsis PUB13 has been shown to attenuate the pattern recognition receptor FLS2-mediated immune signaling by ubiquitinating FLS2 and consequently promoting its degradation by the 26S proteasome. Nevertheless, the cognate ubiquitin-conjugating enzymes (E2) with which PUB13 acts to modulate FLS2-mediated PTI are … how to spice up love lifeWebPUB12 and PUB13 are recruited to the FLS2 complex in response to flg22 (Lu et al., 2011). BAK1 phosphorylation of PUB12/PUB13 leads to FLS2 ubiquitination by the E3 ligases for receptor degradation. Consistent with this, FLS2 signaling outputs and bacterial resistance are enhanced in pub12 pub13 plants. Following ligand-induced association how to spice up kraft dinnerWebJul 13, 2024 · The ARM domains of PUB12/13 are essential for interaction with FLS2–BAK1 complex and phosphorylation by BAK1 ( Zhou et al., 2015a ). In vitro ubiquitination assay showed that PUB12 and PUB13 specifically polyubiquitinate FLS2, but not BAK1 and BIK1, which promotes the degradation of FLS2 ( Lu et al., 2011 ). re4 remake chapter 4 puzzlesWebBAKI phosphorylates PUB12 and PUB13 and is required for FLS2-PUB12/13 association. PUB12 and PUB13 polyubiquitinate FLS2 and promote flagellin-induced FLS2 degradation, and the publ2 and publ3 mutants displayed elevated immune responses to flagellin treatment. Our study has revealed a unique regulatory circuit of direct ubiquitination re4 remake charm list