Can divalproex cause thrombocytopenia

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August undefined, 2024

WebNov 10, 2008 · ITP can be idiopathic, or related to viral infections, autoimmune disorders, lymphoproliferative disorders, or drugs [34, 35]. Classical causes of drug-induced thrombocytopenia are the quinine and quinine-like drugs . The thrombocytopenia is typically sudden, severe, and may be accompanied by bleeding. WebMethods: Patients with refractory partial epilepsy were enrolled in this double-blind, multicenter, concentration-response trial that evaluated the efficacy and safety of high …

Depakote and Depakote ER Side Effects: Mild, Severe, and More

WebApr 19, 2024 · Thrombocytopenia rarely is inherited; or it can be caused by a number of medications or conditions. Whatever the cause, circulating platelets are reduced by one or more of the following processes: … WebNov 14, 2024 · Depakote (divalproex sodium) has many possible side effects. Some of the most common ones are stomach-related problems, headache, and drowsiness. More serious Depakote side effects include liver damage, birth defects, and pancreatitis. Talk to your healthcare provider about the risks and benefits of Depakote before you start it. sign in to publisher rocket

Frequently asked questions (FAQs) Depakote® (divalproex …

WebValproate can cause major congenital malformations, particularly neural tube defects (e.g., spina bifida). ... may be dose-related. The probability of thrombocytopenia appears to increase significantly at total valproate concentrations of ... Stopping divalproex sodium extended-release tablets suddenly can cause serious problems. Divalproex ... WebDrinking a lot of alcohol may cause your platelet level to drop. Toxic chemicals : Exposure to toxic chemicals, including arsenic, benzene and pesticides, may affect your platelet … WebAug 22, 2013 · The case demonstrates thrombocytopenia induced by treatment with valproic acid in a relatively young patient after only a week of treatment. The risk of thrombocytopenia caused by valproic acid is 5%, and the risk increases with the age of the patient and with the level of valproic acid in the blood. 4-6 In this case, the patient was … sign in to quickbooks account

DailyMed - DIVALPROEX SODIUM tablet, film coated, extended …

Valproic Acid (Oral Route) Precautions - Mayo Clinic

WebDivalproex sodium delayed-release tablets are administered orally in divided doses. Divalproex sodium delayed-release tablets should be swallowed whole and should not be crushed or chewed (2.1, 2.2).Mania: Initial dose is 750 mg daily, increasing as rapidly as possible to achieve therapeutic response or desired plasma level ().The maximum … WebSep 23, 2010 · A positive finding provides very strong evidence that drug sensitivity is the cause of thrombocytopenia and can be helpful for understanding the mechanisms of DITP. 26 Because antibody testing is ordered only when a particular drug is suspected of being a possible cause of thrombocytopenia, identification of drug-dependent, platelet … theraband high resistanceWebNov 2, 2024 · Along with its needed effects, divalproex sodium may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need … theraband hep ue

"WebNov 30, 2024 · Patients with DITP develop a drop in platelet count 5 to 10 days after drug administration with an increased risk of hemorrhage. The diagnosis of DITP is often … " - Can divalproex cause thrombocytopenia

Can divalproex cause thrombocytopenia

A Case of Thrombocytopenia Associated With Valproic Acid …

WebDec 19, 2024 · Valproate is an effective anti-epileptic and mood stabilizer drug, but its prescription may be complicated by the development of thrombocytopenia. The … WebDEPAKOTE can cause other serious side effects, including: Bleeding problems: red or purple spots on your skin, bruising, pain and swelling into your joints due to bleeding or bleeding from your mouth or nose. High ammonia levels in your blood: feeling tired, vomiting, changes in mental status.

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WebMar 1, 2024 · Valproic acid is used to treat certain types of seizures (epilepsy). This medicine is an anticonvulsant that works in the brain tissue to stop seizures. Valproic acid is also used to treat the manic phase of bipolar disorder (manic-depressive illness), and helps prevent migraine headaches. WebDec 30, 2024 · It's likely that a routine blood test showing a high platelet count will be your first indication that you have thrombocytosis. Besides taking your medical history, examining you physically and running tests, your doctor might ask about factors that could affect your platelets, such as a recent surgery, a blood transfusion or an infection.

WebNov 2, 2024 · Commonly reported side effects of divalproex sodium include: abdominal pain, asthenia, dizziness, drowsiness, nausea, vomiting, thrombocytopenia, and anorexia. Other side effects include: abnormality in thinking, alopecia, ataxia, nystagmus disorder, tremor, weight loss, fever, and skin rash.

WebThe phase IV clinical study analyzes which people take Depakote and have Thrombocytopenia. It is created by eHealthMe based on reports of 49,884 people who … WebApr 2, 2024 · Thrombocytopenia is a condition that develops because your body does not have enough platelets. Platelets are cells that help your blood to clot. Your body may not be making enough platelets, or it may be destroying too many platelets. When platelets become low, your risk for bleeding increases. Severe bleeding may become life-threatening.

WebFeb 23, 2024 · bleeding problems and low blood platelet levels; high blood ammonia levels; hypothermia ... Depakote or Depakote ER can cause pancreatitis, which can be life …

WebSide Effects. See also Warning section. Diarrhea, dizziness, drowsiness, hair loss, blurred/ double vision, change in menstrual periods, ringing in the ears, shakiness (tremor), … sign in to pubgWebMar 1, 2024 · Thrombocytopenia (low platelet count) or Viral infection (eg, HIV, cytomegalovirus infection)—Use with caution. May make these conditions worse. Liver disease or ... Divalproex sodium may cause serious allergic reactions affecting multiple … Divalproex sodium is used to treat certain types of seizures (epilepsy). This … sign in to publisherWebNov 27, 2024 · Rarely, yes: Most people who take Depakote ( valproic acid) have no impact on their blood. Some people, however, can develop low platelets or low neutrophils or both. Of course, those blood problems may also occur to people taking Depakote but be completely unrelated to the drug. A hematologist is the doctor to sort out the question. theraband hip flexionWebBleeding and other hematopoietic disorders; monitor platelet counts and coagulation tests ( 5.8) ... Stopping divalproex sodium extended-release tablets suddenly can cause serious problems. Divalproex sodium extended-release tablets can cause serious side effects, including: Serious liver damage that can cause death, especially in children ... sign in to ravelryWebDrinking a lot of alcohol may cause your platelet level to drop. Toxic chemicals : Exposure to toxic chemicals, including arsenic, benzene and pesticides, may affect your platelet level. Medications : Antibiotics that treat bacterial infections, medication for seizures and heart conditions, and the blood thinner heparin may affect platelet levels. sign in to quickbooks workforceWebFeb 23, 2024 · Yes, it’s possible for Depakote and Depakote ER to cause long-term side effects. Liver damage, including liver failure, has been reported. Pancreatitis (swelling and damage of the pancreas)... sign in to rackspace emailWeb• Pregnancy: Depakote can cause congenital malformations including neural tube defects. Pregnancy registry available (5.2, 8.1) • Pediatric: Children under the age of two years are at considerably higher risk of fatal hepatotoxicity (5.1, 8.4) • Geriatric: reduce starting dose; increase dosage more slowly; monitor sign into rackspace email